Truth: Red, White & Black, a 2003 miniseries by Robert Morales and Kyle Baker. Published by Marvel Comics.
A story about how the “super serum” used to turn white guy Steve Rogers into Captain America during World War II probably would’ve been tested on black soldiers, most of whom were mutated and killed by the experiments. Inspired by the real-life Tuskegee Experiment.
Republished in 2009 as Captain America: Truth.